Sepsis Articles Published in November-December

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  1. Biochemical-immunological hybrid biosensor based on two-dimensional chromatography for on-site sepsis diagnosis.

Author(s): Kim, Seung-Wan; Cho, Il-Hoon; Lim, Guei-Sam; Park, Gi-Na; Paek, Se-Hwan

Source: Biosensors & bioelectronics; Dec 2017; vol. 98 ; p. 7-14

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Plasma lactoferrin levels in newborn preterm infants with sepsis.

Author(s): Decembrino, Lidia; DeAmici, Mara; De Silvestri, Annalisa; Manzoni, Paolo; Paolillo, Piermichele; Stronati, Mauro

Source: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians; Dec 2017; vol. 30 (no. 23); p. 2890-2893

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Cholangitis Lenta: A Clinicopathologic Study of 28 Cases.

Author(s): Torous, Vanda F; De La Cruz, A Laura; Naini, Bita V; Wang, Hanlin L

Source: The American journal of surgical pathology; Dec 2017; vol. 41 (no. 12); p. 1607-1617

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Gastric perforation after duodenopancreatectomy.

Author(s): Bäcker, Henrik; Beeres, Frank Jp; Rossi, Marco; Scheiwiller, Andreas

Source: Medical mycology case reports; Dec 2017; vol. 18 ; p. 21-23

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. The Physiology of Early Goal-Directed Therapy for Sepsis.

Author(s): Lief, Lindsay; Arbo, John; Berlin, David A

Source: Journal of intensive care medicine; Dec 2017; vol. 32 (no. 10); p. 567-573

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. 6. Nitrite administration improves sepsis-induced myocardial and mitochondrial dysfunction by modulating stress signal responses.

Author(s): Kawaguchi, Ryoichi; Hirata, Naoyuki; Tokinaga, Yasuyuki; Hayashi, Shunsuke; Inoue, Shigeaki; Watanabe, Nobuo; Yamakage, Michiaki

Source: Journal of anesthesia; Dec 2017; vol. 31 (no. 6); p. 885-894

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Predictive value of procalcitonin for diagnosis of infections in patients with chronic kidney disease: a comparison with traditional inflammatory markers C-reactive protein, white blood cell count, and neutrophil percentage.

Author(s): Sun, Yanbei; Jiang, Lijuan; Shao, Xiaonan

Source: International urology and nephrology; Dec 2017; vol. 49 (no. 12); p. 2205-2216

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Sepsis prediction in critically ill patients by platelet activation markers on ICU admission: a prospective pilot study.

Author(s): Layios, Nathalie; Delierneux, Céline; Hego, Alexandre; Huart, Justine; Gosset, Christian; Lecut, Christelle; Maes, Nathalie; Geurts, Pierre; Joly, Arnaud; Lancellotti, Patrizio; Albert, Adelin; Damas, Pierre; Gothot, André; Oury, Cécile

Source: Intensive care medicine experimental; Dec 2017; vol. 5 (no. 1); p. 32

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Increased glucocorticoid receptor expression in sepsis is related to heat shock proteins, cytokines, and cortisol and is associated with increased mortality.

Author(s): Vardas, Konstantinos; Ilia, Stavroula; Sertedaki, Amalia; Charmandari, Evangelia; Briassouli, Efrossini; Goukos, Dimitris; Apostolou, Kleovoulos; Psarra, Katerina; Botoula, Efthimia; Tsagarakis, Stylianos; Magira, Eleni; Routsi, Christina; Stratakis, Constantine A; Nanas, Serafim; Briassoulis, George

Source: Intensive care medicine experimental; Dec 2017; vol. 5 (no. 1); p. 10

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Baseline thrombospondin-1 concentrations are not associated with mortality in septic patients: a single-center cohort study on the intensive care unit.

Author(s): van der Wekken, Ruben J; Kemperman, Hans; Roest, Mark; de Lange, Dylan W

Source: Intensive care medicine experimental; Dec 2017; vol. 5 (no. 1); p. 7

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Erratum to: Heparin-binding protein is important for vascular leak in sepsis.

Author(s): Bentzer, Peter; Fisher, Jane; Kong, HyeJin Julia; Mörgelin, Mattias; Boyd, John H; Walley, Keith R; Russell, James A; Linder, Adam

Source: Intensive care medicine experimental; Dec 2017; vol. 5 (no. 1); p. 6

Publication Date: Dec 2017

Publication Type(s): Published Erratum

 

  1. Soluble Toll-like receptor 2 is a biomarker for sepsis in critically ill patients with multi-organ failure within 12 h of ICU admission.

Author(s): Holst, Benjamin; Szakmany, Tamas; Raby, Anne-Catherine; Hamlyn, Vincent; Durno, Kimberley; Hall, Judith E; Labéta, Mario O

Source: Intensive care medicine experimental; Dec 2017; vol. 5 (no. 1); p. 2

Publication Date: Dec 2017

Publication Type(s): Letter

 

  1. Sepsis in Older Adults.

Author(s): Rowe, Theresa A; McKoy, June M

Source: Infectious disease clinics of North America; Dec 2017; vol. 31 (no. 4); p. 731-742

Publication Date: Dec 2017

Publication Type(s): Journal Article Review

 

  1. Neutropenic Fever.

Author(s): White, Lindsey; Ybarra, Michael

Source: Hematology/oncology clinics of North America; Dec 2017; vol. 31 (no. 6); p. 981-993

Publication Date: Dec 2017

Publication Type(s): Journal Article Review

 

  1. Intermediate-term and long-term mortality among acute medical patients hospitalized with community-acquired sepsis: a population-based study.

Author(s): Henriksen, Daniel P; Pottegård, Anton; Laursen, Christian B; Jensen, Thøger G; Hallas, Jesper; Pedersen, Court; Lassen, Annmarie T

Source: European journal of emergency medicine : official journal of the European Society for Emergency Medicine; Dec 2017; vol. 24 (no. 6); p. 404-410

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Septic shock resuscitation in the first hour.

Author(s): Simpson, Nicholas; Lamontagne, Francois; Shankar-Hari, Manu

Source: Current opinion in critical care; Dec 2017; vol. 23 (no. 6); p. 561-566

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Assessment of sepsis-induced immunosuppression at ICU discharge and 6 months after ICU discharge.

Author(s): Zorio, Violette; Venet, Fabienne; Delwarde, Benjamin; Floccard, Bernard; Marcotte, Guillaume; Textoris, Julien; Monneret, Guillaume; Rimmelé, Thomas

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 80

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Red blood cell transfusion in the resuscitation of septic patients with hematological malignancies.

Author(s): Mirouse, Adrien; Resche-Rigon, Matthieu; Lemiale, Virginie; Mokart, Djamel; Kouatchet, Achille; Mayaux, Julien; Vincent, François; Nyunga, Martine; Bruneel, Fabrice; Rabbat, Antoine; Lebert, Christine; Perez, Pierre; Renault, Anne; Meert, Anne-Pascale; Benoit, Dominique; Hamidfar, Rebecca; Jourdain, Mercé; Darmon, Michaël; Azoulay, Elie; Pène, Frédéric; Groupe de Recherche sur la Réanimation Respiratoire en Onco-Hématologie (Grrr-OH)

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 62

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Low HDL levels in sepsis versus trauma patients in intensive care unit.

Author(s): Tanaka, Sébastien; Labreuche, Julien; Drumez, Elodie; Harrois, Anatole; Hamada, Sophie; Vigué, Bernard; Couret, David; Duranteau, Jacques; Meilhac, Olivier

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 60

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Omega-3 supplementation in patients with sepsis: a systematic review and meta-analysis of randomized trials.

Author(s): Lu, Clara; Sharma, Sunjay; McIntyre, Lauralyn; Rhodes, Andrew; Evans, Laura; Almenawer, Saleh; Leduc, Lori; Angus, Derek C; Alhazzani, Waleed

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 58

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. The impact of a multifaceted intervention including sepsis electronic alert system and sepsis response team on the outcomes of patients with sepsis and septic shock.

Author(s): Arabi, Yaseen M; Al-Dorzi, Hasan M; Alamry, Ahmed; Hijazi, Ra’ed; Alsolamy, Sami; Al Salamah, Majid; Tamim, Hani M; Al-Qahtani, Saad; Al-Dawood, Abdulaziz; Marini, Abdellatif M; Al Ehnidi, Fatimah H; Mundekkadan, Shihab; Matroud, Amal; Mohamed, Mohamed S; Taher, Saadi

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 57

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure.

Author(s): Martin-Loeches, Ignacio; Muriel-Bombín, Arturo; Ferrer, Ricard; Artigas, Antonio; Sole-Violan, Jordi; Lorente, Leonardo; Andaluz-Ojeda, David; Prina-Mello, Adriele; Herrán-Monge, Ruben; Suberviola, Borja; Rodriguez-Fernandez, Ana; Merino, Pedro; Loza, Ana M; Garcia-Olivares, Pablo; Anton, Eduardo; Tamayo, Eduardo; Trapiello, Wysali; Blanco, Jesús; Bermejo-Martin, Jesús F; GRECIA group

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 44

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Sepsis risk factors in infants with congenital diaphragmatic hernia.

Author(s): Levy, Michaël; Le Sache, Nolwenn; Mokhtari, Mostafa; Fagherazzi, Guy; Cuzon, Gaelle; Bueno, Benjamin; Fouquet, Virginie; Benachi, Alexandra; Eleni Dit Trolli, Sergio; Tissieres, Pierre

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 32

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients: a proof-of-concept study.

Author(s): Alegría, Leyla; Vera, Magdalena; Dreyse, Jorge; Castro, Ricardo; Carpio, David; Henriquez, Carolina; Gajardo, Daniela; Bravo, Sebastian; Araneda, Felipe; Kattan, Eduardo; Torres, Pedro; Ospina-Tascón, Gustavo; Teboul, Jean-Louis; Bakker, Jan; Hernández, Glenn

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 29

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Multi-marker approach using procalcitonin, presepsin, galectin-3, and soluble suppression of tumorigenicity 2 for the prediction of mortality in sepsis.

Author(s): Kim, Hanah; Hur, Mina; Moon, Hee-Won; Yun, Yeo-Min; Di Somma, Salvatore; GREAT Network

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 27

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. IL-6 rs1800795 polymorphism is associated with septic shock-related death in patients who underwent major surgery: a preliminary retrospective study.

Author(s): Jiménez-Sousa, Maria Angeles; Medrano, Luz Maria; Liu, Pilar; Fernández-Rodríguez, Amanda; Almansa, Raquel; Gomez-Sanchez, Esther; Ortega, Alicia; Heredia-Rodríguez, María; Gómez-Pesquera, Estefanía; Tamayo, Eduardo; Resino, Salvador

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 22

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Epidemiology of sepsis in Catalonia: analysis of incidence and outcomes in a European setting.

Author(s): Yébenes, Juan Carlos; Ruiz-Rodriguez, Juan Carlos; Ferrer, Ricard; Clèries, Montserrat; Bosch, Anna; Lorencio, Carol; Rodriguez, Alejandro; Nuvials, Xavier; Martin-Loeches, Ignacio; Artigas, Antoni; SOCMIC (Catalonian Critical Care Society) Sepsis Working Group

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 19

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Associations among left ventricular systolic function, tachycardia, and cardiac preload in septic patients.

Author(s): Lanspa, Michael J; Shahul, Sajid; Hersh, Andrew; Wilson, Emily L; Olsen, Troy D; Hirshberg, Eliotte L; Grissom, Colin K; Brown, Samuel M

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 17

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity.

Author(s): Andaluz-Ojeda, David; Nguyen, H Bryant; Meunier-Beillard, Nicolas; Cicuéndez, Ramón; Quenot, Jean-Pierre; Calvo, Dolores; Dargent, Auguste; Zarca, Esther; Andrés, Cristina; Nogales, Leonor; Eiros, Jose María; Tamayo, Eduardo; Gandía, Francisco; Bermejo-Martín, Jesús F; Charles, Pierre Emmanuel

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 15

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Early risk factors and the role of fluid administration in developing acute respiratory distress syndrome in septic patients.

Author(s): Seethala, Raghu R; Hou, Peter C; Aisiku, Imoigele P; Frendl, Gyorgy; Park, Pauline K; Mikkelsen, Mark E; Chang, Steven Y; Gajic, Ognjen; Sevransky, Jonathan

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 11

Publication Date: Dec 2017

Publication Type(s): Journal Article

 

  1. Impact of transfusion on patients with sepsis admitted in intensive care unit: a systematic review and meta-analysis.

Author(s): Dupuis, Claire; Sonneville, Romain; Adrie, Christophe; Gros, Antoine; Darmon, Michael; Bouadma, Lila; Timsit, Jean-François

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 5

Publication Date: Dec 2017

Publication Type(s): Journal Article Review

 

  1. Fluid resuscitation in human sepsis: Time to rewrite history?

Author(s): Byrne, Liam; Van Haren, Frank

Source: Annals of intensive care; Dec 2017; vol. 7 (no. 1); p. 4

Publication Date: Dec 2017

Publication Type(s): Journal Article Review

 

  1. Sepsis biomarkers reprofiling to predict stroke-associated infections.

Author(s): Bustamante, Alejandro; García-Berrocoso, Teresa; Penalba, Anna; Giralt, Dolors; Simats, Alba; Muchada, Marian; Zapata, Elena; Rubiera, Marta; Montaner, Joan

Source: Journal of neuroimmunology; Nov 2017; vol. 312 ; p. 19-23

Publication Date: Nov 2017

Publication Type(s): Journal Article

 

  1. Improving door-to-needle times for patients with suspected neutropenic sepsis.

Author(s): Wild, Tracy

Source: Emergency nurse : the journal of the RCN Accident and Emergency Nursing Association; Nov 2017; vol. 25 (no. 7); p. 24-30

Publication Date: Nov 2017

Publication Type(s): Journal Article

 

  1. Lactate improves SAPS 3 prognostication.

Author(s): Andersson, P; Frigyesi, A

Source: Acta anaesthesiologica Scandinavica; Nov 2017

Publication Date: Nov 2017

Publication Type(s): Journal Article

 

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Quality Improvement Initiative for Severe Sepsis and Septic Shock Reduces 90-Day Mortality: A 7.5-Year Observational Study*

Critical Care Medicine 45(2), February 2017, p 241–252

This study investigates the impact of a quality improvement initiative for severe sepsis and septic shock focused on the resuscitation bundle on 90-day mortality. Furthermore, effects on compliance rates for antiinfective therapy within the recommended 1-hour interval are evaluated. The article concludes, that the continuous quality improvement initiative focused on the resuscitation bundle was associated with increased compliance and a persistent reduction in 90-day mortality over a 7.5-year period. Based on the observational study design, a causal relationship cannot be proven, and respective limitations need to be considered.

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

Critical Care Medicine Volume 45(3), March 2017, p 486–552

A consensus committee of 55 international experts representing 25 international organisations was convened to provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012.”

The panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations, and 18 were best-practice statements. No recommendation was provided for four questions. In conclusion, substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.

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Sepsis and Septic Shock: Current Treatment Strategies and New Approaches

The Eurasian Journal of Medicine. 2017 Feb;49(1):53-58

Many studies have been conducted on sepsis that cause shock, multiorgan dysfunction, and organ failure by especially leading to hemodynamic changes. In sepsis, increasing antibiotic resistance and medicine-resistant hemodynamic changes have resulted in further research on new treatment modalities in addition to classical treatments. In the last decade, the sepsis physiopathology has been elucidated. Various therapeutic agents have been used in addition to antibiotherapy, but no satisfactory results have been obtained. This review summarizes the sepsis pathophysiology, current treatment protocols, and new approaches.

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Protocol Adherence for Severe Sepsis and Septic Shock Management in the Emergency Department; a Clinical Audit.

Emergency. 2017; 5 (1): e16

This study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ED) according to the present standard guidelines.  This is a prospective audit on approaching adult septic patients who were admitted to ED. The audit checklist was created based on the protocols of Surviving Sepsis Campaign and British Royal College recommendations.

The article concludes that protocol adherence in management of severe sepsis and septic shock for urine output measurement, central venous pressure monitoring, administration of inotrope agents, blood transfusion, intravenous antibiotic and hydration therapy, and high flow O2 delivery were disappointingly low. It seems training workshops and implementation of Clinical audit can improve residents’ adherence to current standard guidelines regarding severe sepsis and septic shock

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

Intensive Care Med. 2017 Jan 18. doi: 10.1007/s00134-017-4683-6. [Epub ahead of print]

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A consensus committee of 55 international experts representing 25 international organizations was convened to provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012. The panel consisted of five sections: hemodynamics, infection, adjunctive therapies, metabolic, and ventilation. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable. In conclusion, substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.