Case Study: Incorporating NICE guidance into the Sepsis Care Pathway at Tameside

Tameside and Glossop Integrated Care NHS Foundation Trust published a case study in  January 2017 – Incorporating NICE guidance into the Sepsis Care Pathway at Tameside: improving patient care, safety and mortality in relation to sepsis.


To read more click here.


NICE Guideline (NG51)- Sepsis: recognition, diagnosis and early management

Updated in September 2017 NICE have produced guidelines on sepsis including:
•Recommendations on identifying and assessing people with suspected sepsis, risk factors and risk stratification for sepsis and managing suspected sepsis in acute hospital settings and out of hospital
•Tools and resources to help put the guidance into practice
•Information for the public.

To view full guideline click here

NHS England Produces Sepsis Guidance Implementation Advice for Adults

NHS England has worked with NICE using their guidance and with a group of sepsis experts and the UK Sepsis Trust to produce an operational definition that fits with use of the National Early Warning Score in assessing patients who are acutely unwell (Sepsis guidance implementation advice for adults – NHS England)


Access full document here

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

Critical Care Medicine Volume 45(3), March 2017, p 486–552

A consensus committee of 55 international experts representing 25 international organisations was convened to provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012.”

The panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. Overall, 32 were strong recommendations, 39 were weak recommendations, and 18 were best-practice statements. No recommendation was provided for four questions. In conclusion, substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality.

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Protocol Adherence for Severe Sepsis and Septic Shock Management in the Emergency Department; a Clinical Audit.

Emergency. 2017; 5 (1): e16

This study was aimed to audit the management of severe sepsis and septic shock patients in emergency department (ED) according to the present standard guidelines.  This is a prospective audit on approaching adult septic patients who were admitted to ED. The audit checklist was created based on the protocols of Surviving Sepsis Campaign and British Royal College recommendations.

The article concludes that protocol adherence in management of severe sepsis and septic shock for urine output measurement, central venous pressure monitoring, administration of inotrope agents, blood transfusion, intravenous antibiotic and hydration therapy, and high flow O2 delivery were disappointingly low. It seems training workshops and implementation of Clinical audit can improve residents’ adherence to current standard guidelines regarding severe sepsis and septic shock

Follow this link for the full article